PRESS RELEASES

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November 14, 2012 - Fast Relief of Migraine Pain Achieved with New OptiNose Migraine Treatment, Phase III Clinical Data Show Headache Relief Begins as Early as 15 Minutes After Administration of New OptiNose Migraine Treatment
November 8, 2012 - OptiNose Receives Grant to Fund Nose-to-Brain Research in Autism Spectrum Disorders
October 18, 2012 - Study Shows OptiNose Bi-Directional™ Nasal Technology Reaches Target Areas of the Nasal Cavity Much More Effectively Than Traditional Nasal Spray
October 2, 2012 - Popular Migraine Medicine Quickly Absorbed When Delivered With Novel Breath Powered OptiNose Bi-Directional™ Nasal Technology, New Comparative Data Demonstrates
February 14, 2012 - OptiNose Announces First Patient Enrolled in Phase III Study of Sumatriptan Powder Delivered Intranasally with Innovative Bi-directional Device
February 2, 2012 - OptiNose Files Investigational New Drug Application to use Sumatriptan Delivered with its Novel Drug Delivery Technology