Peter K. Miller
Chief Executive Officer, Board of Directors
Peter Miller has served on the OptiNose Board of Directors since 2008, at which time he became familiar with OptiNose’s unique approach, and convinced of the significant potential of the product. After leading a significant capital raise that allowed OptiNose to move forward with clinical trials and the commercialization process in 2009, Mr. Miller accepted the role of CEO in 2010. He remains a member of the Company’s Board of Directors.
Mr. Miller was previously the Co-Founder, CEO and President of Take Care Health Systems, a company that through a revolutionary idea to operate medical clinics inside Walgreen’s retail pharmacies, is disrupting the U.S. Healthcare system. Miller served as a vice president in the Walgreen’s Health and Wellness Division and remained CEO for Take Care Health Systems for three years after its sale to Walgreen’s, while growing the clinic operation to more than 400 clinics nationwide.
Earlier, Mr. Miller spent more than 15 years at Johnson & Johnson, serving in a variety of marketing and general management roles that included Worldwide President of Johnson & Johnson – Merck Consumer Pharmaceuticals, and of Janssen Pharmaceutica, a $4 billion dollar pharmaceutical company. While at J&J, he played an integral role in building brands such as Tylenol, Motrin, Imodium, Pepcid, Duragesic, Risperdal and Aciphex.
Mr. Miller earned an economics degree from Trinity College and an MBA from the Kellogg School of Management at Northwestern University.
Ramy A. Mahmoud, M.D., M.P.H.
President and Chief Operating Officer
Dr. Mahmoud joined OptiNose in 2010, playing a key role establishing its U.S. presence, and today is responsible for all aspects of company’s operation, including corporate strategy, research and development, manufacturing and supply chain, financial management, commercial and business development.
Dr. Mahmoud previously spent 14 years at Johnson & Johnson, where he was Chief Medical Officer and a member of the Global Management Board of the Ethicon group of companies. During his J&J tenure, he also held senior roles in the Pharmaceutical sector: in addition to management board responsibilities at several global and U.S. operating companies, he led a range of functions in both R&D and Commercial organizations. Ramy participated in the development, launch and/or commercialization of dozens of pharmaceutical and medical device products spanning multiple therapeutic categories, including blockbusters such as RISPERDAL®, DURAGESIC® and CONCERTA®.
Earlier in his career, Dr. Mahmoud earned the rank of Lieutenant Colonel in the United States Army, serving 10 years on active duty and an additional 10 years in the Army Reserves. As both a battalion and flight surgeon, he received numerous commendations and decorations. His government service also encompassed various academic, patient care, and research positions, culminating as head of the Department of Epidemiology at the Walter Reed Army Institute of Research, and inaugural leader of a policy research and analysis activity in support of the Assistant Secretary of Defense (Health Affairs).
Dr. Mahmoud is an accomplished international scientist, having published more than 50 peer-reviewed papers and textbook chapters, and serving as a scientific reviewer for a number of journals and textbooks.
Ramy earned a Master of Healthcare Management & Policy from the Harvard School of Public Health, an M.D. from the first Honors Program in Medical Education at the University of Miami, and board certification in both Public Health/Preventive Medicine and in Internal Medicine. He has been and remains involved with numerous professional societies.
Chief Commercial Officer
Tom Gibbs joined OptiNose in September 2016 as Chief Commercial Officer. In this role, Mr. Gibbs has responsibility for all activities associated with the commercial function of the company and has executive oversight of business development.
Mr. Gibbs brings more than 20 years of diverse commercial leadership experience to OptiNose, including roles in general management, marketing, sales, commercial operations, customer insights, analytics, and finance. He joined OptiNose from Takeda Pharmaceuticals, where he led the General Medicines Business Unit for the United States. In this role, Gibbs had responsibility for a multi-billion dollar portfolio comprised of 11 brands spanning several therapeutic classes including CNS, GI, inflammation, diabetes, and metabolics, and led a team of over 2,000 people.
Before joining Takeda, Mr. Gibbs was at Vanda Pharmaceuticals, where he was the Chief Commercial Officer for the US and EU commercial organizations, including the rare disease franchise and CNS portfolio. Prior to joining Vanda, Mr. Gibbs spent more than five years at Bristol-Myers Squibb, where he held a variety of commercial leadership roles of increasing responsibility. Most recently, Mr. Gibbs served as the Vice President of Worldwide Commercial Operations, where he helped drive the transformation of the company’s commercial model and commercial organization across all therapeutic categories and geographies.
Prior to working at Bristol-Myers Squibb, Mr. Gibbs was the Vice President of US Sales for Novartis Vaccines & Diagnostics, where he led the launch of two new vaccines, designed and deployed a pediatric sales force, developed and implemented a supply chain solution to support a direct distribution business model, and created a sales operations infrastructure to support an expanded sales force. Earlier in his career, Mr. Gibbs held multiple US and global marketing roles at SmithKline Beecham (now GSK), Johnson & Johnson, and Endo Pharmaceuticals.
Tom holds a BS in economics with a dual concentration in finance and marketing and an MBA from the Wharton School of the University of Pennsylvania
Chief Financial Officer
Keith Goldan joined OptiNose in January 2017 as Chief Financial Officer. He brings to the company more than 25 years of executive financial and operational leadership in biopharmaceutical and medical technology companies including CFO roles at private and public life sciences companies from early through commercial stage. Mr. Goldan most recently served as Senior Vice President and Chief Financial Officer at Fibrocell, a publicly-held cell and gene therapy company, and of NuPathe, where he helped direct the sale of the specialty pharmaceutical company to Teva in 2014. In these roles, Mr. Goldan led finance, IT, HR and corporate development teams and successfully raised capital though an IPO as well as multiple follow-on equity, rights, private placement and debt offerings.
Mr. Goldan’s experience also includes CFO roles at PuriCore (now Realm Therapeutics) and Biosyn as well as of roles with ViroPharma and KPMG.
Keith holds a BS (cum laude) in finance from the Robert H. Smith School of Business at the University of Maryland and an MBA from the Wharton School of Business at the University of Pennsylvania.
Chief Legal Officer
Michael Marino joined OptiNose in January 2017 as our Chief Legal Officer. In this role, Mr. Marino will serve as Corporate Secretary to the Board of Directors and have overall responsibility for leading the legal function including legal and intellectual property strategy, risk management, compliance, contracting and advising the Company on strategic transactions, financings and corporate governance matters.
Mr. Marino is a seasoned executive and legal advisor with more than 15 years of experience advising public and privately-held companies in a diverse range of industries – most notably life sciences. Prior to joining OptiNose, Mr. Marino served as Senior Vice President, General Counsel and Corporate Secretary of Fibrocell Science, Inc., a publicly-held cell and gene therapy company. Prior to Fibrocell, Mr. Marino served as Senior Vice President, General Counsel and Corporate Secretary of NuPathe Inc., a publicly-held specialty pharmaceutical company, from 2010 until its acquisition by Teva Pharmaceuticals in 2014. During his tenure at Fibrocell and NuPathe, Mr. Marino secured the issuance of numerous U.S. and foreign patents, successfully managed litigation matters, implemented and enhanced compliance programs, and led the legal negotiations for public and private financing transactions, licensing and collaboration arrangements and the sale of NuPathe.
Before joining NuPathe, Mr, Marino was an attorney at the law firms of Morgan, Lewis & Bockius LLP in Philadelphia, PA and WilmerHale LLP in Boston, MA where his practice focused on mergers and acquisitions, collaborations, financing transactions, corporate governance, securities and other general corporate matters.
Michael holds a Juris Doctor from Boston College Law School and a Bachelor of Science in Accountancy from Villanova University.
Ramona Lloyd, Ph.D., RAC
Vice President of Regulatory and Quality
Ramona Lloyd, Ph.D. is Vice President, Regulatory Affairs and Quality at OptiNose. In this role, Dr. Lloyd is responsible for regulatory strategy and quality in support of development and commercialization activities.
A regulatory professional for more than 20 years, Dr. Lloyd has led or participated in the submission of numerous global investigational applications and successful marketing applications for small molecules, biologics and devices across multiple therapeutic areas.
Prior to joining OptiNose, she served as both a consultant to the pharmaceutical industry and as an executive with Sanofi-Aventis, Bristol Myers-Squibb, and Johnson and Johnson. She acted as Sr. Vice President of Regulatory Affairs and Safety for ImClone Systems and has served as Vice President of Regulatory Affairs and Quality for public and private biotechs, leading global regulatory strategy, regulatory submissions through product approval and key meetings with global regulatory authorities.
Dr. Lloyd earned a doctorate in Molecular Genetics and Microbiology from Rutgers University – Robert Wood Johnson Medical School, and was a researcher at the Center for Advanced Biotechnology and Medicine. She earned the professional credential in regulation of healthcare products, Regulatory Affairs Certified (RAC).
Vice President, Finance
Michele Janis joined OptiNose in 2011 as Vice President, Finance and is responsible for managing all accounting and finance activities within the Company.
With more than 15 years of accounting and financial management expertise, Janis previously held the role of Director of Business Analysis and Planning at Take Care Health Systems, a Walgreens Company, where she was responsible for leading financial and business analytics for strategic initiatives.
Prior to joining Take Care Health Systems, Ms. Janis simultaneously served as CFO/Controller to several pharmaceutical and technology-based early stage companies, after which she joined The National Digital Medical Archive, which specialized in medical imaging storage and analytics technology. Earlier in her career, Janis was the CFO for Creative Labs’ OEM division, a worldwide leader in products for the personal computer industry. She also served as Corporate Controller for Atlantic Dairy Cooperative, a milk distributor and dairy products manufacturer
Ms. Janis holds an MBA in Finance from La Salle University, and a Bachelor of Science in Accounting from West Chester University.
John Messina, Pharm.D.
Vice President, Clinical Development
John Messina is the Vice President of Clinical Development for OptiNose. He joined the company in 2010 and leads the development and implementation of all clinical programs, as well as clinical components of regulatory submissions and interactions with regulatory agencies.
Prior to joining OptiNose, Dr. Messina served as Vice President of Clinical Operations and Strategic Planning at Cephalon, Inc. where he led the development, planning and execution of all company clinical programs across therapeutic areas. Additionally, Mr. Messina has worked at Purdue Pharma L.P., Novartis Pharmaceuticals Corp. and Sandoz Pharmaceutical Corp. He has conducted clinical trials in all phases of development and served as a clinical lead for multiple NDA submissions and product launches.
John earned a Doctor of Pharmacy Degree from Purdue University in West Lafayette, Indiana, and completed an Industrial Clinical Pharmacy Fellowship at Rutgers University, in New Brunswick, New Jersey. He has published extensively within the fields of analgesia and CNS clinical research.
Vice President, Manufacturing and Supply Chain
Bob Useller joined Optinose in 2010 and today serves as Vice President, Manufacturing and Supply Chain. Bob is responsible for third party supplier selection and contract development, material procurement, commercial manufacturing, logistics, inventory management and the distribution of OptiNose products.
Previously, Useller served as the Vice President of Supply Chain Management at Aton Pharma, Inc., where he was responsible for the identification, selection and management of a number of contract manufacturers and third party service providers. Mr. Useller also spent more than 30 years at Johnson & Johnson where he held leadership positions in logistics, package development, procurement and manufacturing.
Useller holds a Bachelor of Arts in Biology from La Salle University.
Vice President, Operations & Program Management
Sheila Bergey is Vice President of Operations & Program Management. With a track record of strategically repositioning organizations, building teams and driving the execution that brings about new levels of performance across a range of disciplines, she is uniquely qualified to lead this integrated function.
Most recently, Ms. Bergey was with MannKind Corporation, a biopharmaceutical company focused on developing drug-device combination-product technologies. Previously, over 25 years with Johnson & Johnson, she held leadership positions in Operations/Supply Chain, served as CIO for multiple operating companies, and was the VP of Change Management – a role combining Strategic Planning, Program Management, IT, Process Excellence and Procurement. She also founded Saybrook Consulting and served as COO of Lindi Skin, a skin care company in the Philadelphia area.
Ms. Bergey holds an MBA from Temple University and a Bachelor of Science in Business Administration – Operations Management from Drexel University.
Per G. Djupesland, M.D., Ph.D.
Per G. Djupesland, M.D., Ph.D.
Co-Founder and Chief Scientific Officer of OptiNose AS
Per G Djupesland, M.D., Ph.D. is the inventor of OptiNose’s patented, bi-directional nasal drug delivery technology and is a Co-Founder. Dr. Djupesland is a lead inventor on all 39 OptiNose patent families/patent applications, and serves as Chief Scientific Officer of OptiNose AS, with primary responsibility for device discovery and early development efforts. These early development efforts include identifying new product opportunities that use bi-directional technology, advancing the design of devices using the bi-directional technology to treat a variety of medical conditions and conducting Phase I and IIa trials with new “nose-to-brain” applications for the technology.
Dr. Djupesland is an Otolaryngologist (ENT) with a specialization in rhinology and more than 25 years of clinical experience. Among other positions prior to OptiNose, he served as a Clinical Research Fellow at the Hospital for Sick Children and Toronto General in Toronto, Canada, primarily studying the role of nitric oxide in the upper airways. Dr. Djupesland has authored more than 50 peer reviewed articles in international medical journals and has lectured at numerous international scientific conferences.
He earned medical and doctorate degrees in the field of nasal physiology and aerodynamics from the University of Oslo.
Helena Kyttari Djupesland
Helena Kyttari Djupesland
Co-Founder and Co-Chief Executive Officer of OptiNose AS (Norway)
Ms. Djupesland helped to found OptiNose AS in Norway and during the period from 2000-2010 she raised funds, negotiated venture capital deals, led recruiting efforts and was responsible for managing clinical development for Phase I and IIa studies. Ms. Djupesland’s current responsibilities include administration of on-going new product development efforts in device discovery and early development research conducted by OptiNose AS. Her responsibilities entail managing research vendor contracts, grant funding, project plans and timelines, and serving as an R&D project manager for early phase clinical trials. She also plays a role in management of the company’s patent portfolio.
Prior to OptiNose, Helena spent five years as Vice President, Operations at Kvaerner Energy, Thermal Power, (acquired by GE Company) where she was responsible for Project Management, Engineering, Procurement and Manufacturing. She also spent nine years at Storebrand International Reinsurance, the largest insurance company in Norway, gaining extensive experience in international business, risk evaluations and negotiating and closing deals.
Ms. Djupesland graduated from the Law School at the University of Athens, earned a Master in Administrative Science from the University of Paris II and an MBA from the Norwegian School of Management. She is fluent in four languages.