Powder Delivery Device

OptiNose’s breath-powered nasal delivery technology significantly improves delivery to the target sites deep into the nasal cavity. The powder delivery device has a disposable drug-containing section and a reusable device body that can be packaged along with a number of drug-containing sections. The disposable drug-containing sections contains the powdered drug within standard size 3 inhalation capsules.

To operate the powder delivery device, a disposable section is inserted into the device body and the piercing button on the side is depressed once. Two steel pins connected to the button pierce the capsule and are automatically retracted by spring action when the button is released. The user slides the nosepiece of the device into the nostril and the mouthpiece is inserted between the lips. The user then takes a deep breath closes the lips around the mouthpiece and exhales, delivering drug into the nasal cavity.

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User studies have shown a clear preference over traditional nasal sprays.

• Intuitive and easy to use
• More comfortable because of its fixed position during use
• Airflow through the nose at actuation reduces the discomfort often experienced when the spray is released
• Reduction in the aftertaste at the back of the throat